Neuroendocrine Blockade of the Reproductive Axis in Female Athletes

This review aims at defining the neuroendocrine mechanisms underlying sport-induced restrictions of reproductive axis in female athletes. Episodic gonadotropin release was found to be compromised, presumably a result impaired hypothalamic pulsatile GnRH release. Any deviation from optimal may suboptimal function ovaries, leading disorders menstrual cycle and ovulation. A whole spectrum dysfunctions ranging ovulatory eumenorrhea luteal phase defects amenorrhea has been reported sportive women. As essential factors these observations, activation adrenal altered central nervous neurotransmitter activity have identified transfer metabolic, nutritional, stress signals into The degree by which governing reproduction is critically depends on intensity duration exercise state training. Other decisive energy expenditure availability, nutritional components, maturity hypothalamic-pituitary-ovarian (HPO) when sport initiated. In conclusion, gradual cessation observed athletes interpreted as an adaptive mechanism response physical psychological endurance during sport. restriction capacity serve protection (endogenous contraception) preserve woman’s health.